Microbiological Profile and Antimicrobial Susceptibility of Bloodstream Infections in Pediatric Patients at a Tertiary Care Hospital

Abstract

Bloodstream infections (BSIs) in pediatric populations are associated with high morbidity and mortality, especially in healthcare settings where antimicrobial resistance (AMR) is on the rise. This study investigates the microbiological profile and antimicrobial susceptibility of BSIs among pediatric patients at a tertiary care hospital over two years, analyzing data from 500 cases. We assess pathogen prevalence, susceptibility patterns, patient demographics, seasonal trends, and clinical outcomes. Findings reveal a predominance of Escherichia coli and Klebsiella pneumoniae, both exhibiting high resistance to beta-lactams and other first-line antibiotics. The study underscores the need for targeted antibiotic stewardship, updated empiric treatment guidelines, and robust infection control measures in pediatric care.