Study On Role of Cerebroplacental Ratio in Predicting Adverse Fetal Outcome from A Tertiary Care Teaching Hospital Of Madhya Pradesh

Abstract

Background: The following study detects at-risk fetuses susceptible to hypoxia, especially among an ostensibly low-risk group prior to the commencement of labor. The cerebroplacental ratio (CPR) is becoming a significant predictor of adverse pregnancy outcomes. Aim: This study aims to evaluate the role of CPR in predicting adverse fetal outcomes during pregnancy by assessing its association with selected perinatal outcomes.
Methods: The study was a prospective observational investigation conducted in a hospital setting. Following the acquisition of informed consent from the patient, history-taking and examination, prenatal ultrasound with color Doppler for the calculation of CPR was performed. Results: The mean age of the participant was 27.4 years. Abnormal cerebroplacental ratio (CPR) was observed in 26.7% (n = 20) of the cases. 70% (n = 14) of women with an abnormal CPR required a cesarean section for fetal distress, compared to 18.2% (n = 10) of those with a normal CPR. CPR had a sensitivity of 55% (n = 11) and a specificity of 100% (n = 55), with a positive predictive value (PPV) of 100% (n = 20) and a negative predictive value (NPV) of 60% (n = 33). Conclusion: The high specificity and positive predictive value of CPR suggest that individuals with a normal CPR are at a significantly reduced risk of adverse perinatal outcome. Consequently, deliveries for these individuals may be safely conducted at peripheral centers. In contrast, those with a low CPR should be promptly referred to a higher-level facility equipped for comprehensive fetal monitoring during the intrapartum period, along with access to a neonatal unit.