Hematological Parameters for Predicting Failure of Thrombolytic Therapy after ST-Elevation Myocardial Infarction

Abstract

Aim: To predict the failure of thrombolytic therapy by hematological parameters after ST-Elevation myocardial infarction.
Material and methods: A total of 41 patients with failed thrombolysis and 31 patients with successful thrombolysis after ST-elevation myocardial infarction were taken. Hemoglobin concentration, red blood cell count, red cell distribution width, white blood count, Neutrophil %, Lymphocyte %, Neutrophil/lymphocyte ratio, platelet count, mean platelet volume, platelet distribution width, large platelet concentration ratio, HBA1c, and Troponin I was taken. Results: The mean age of patients with failed thrombolysis was higher than the patients with successful thrombolysis (56.02 ± 11.2 vs 44.6 ± 11.6, p < 0.05). The heart rate, hemoglobin concentration, red blood cell count and eutrophil/lymphocytic ratio of patients belonging to a group with failed thrombolysis were significantly less than that of successful thrombolysis group. Conclusion: Among hematological parameters, hemoglobin concentration, red blood cell count, and neutrophillymphocyte ratio can be used to predict the successfulness of thrombolytic therapy.