DISSEMINATED CRYPTOCOCCUS: AN UNUSUAL PRESENTATION-A CASE REPORT

Abstract

Introduction: Cryptococcosis is a fungal disease affecting the respiratory and central nervous
system in HIV-infected individuals, causing life-threatening symptoms and necessitating prompt diagnosis, with approximately 5% of infected individuals developing it. Case Report: A 35-year-old HIV-positive male patient presented with abdominal pain, fever, and cough, without cervical lymphadenopathy. USG revealed multiple enlarged lymph nodes, and FNAC was performed.
Result: Cytological examination revealed lymphocytes, histiocytes, granulomas, and necrotic
material, along with budding yeast of Cryptococcus neoformans. PAS, GMS, Indian ink, CSF,
and bone marrow tests confirmed Cryptococci.
Conclusion: FNAC is a safe and efficient technique for early diagnosis of Cryptococcal
lymphadenitis, a rare presentation in lymphadenopathy, highlighting its potential for rapid
treatment.