Journal of Cardiovascular Disease Research (J Cardiovasc. Dis. Res.) [www.jcdronline.org] J Cardiovasc. Dis. Res. [ISSN: Print -0975-3583, Online - 0976-2833] is a double-blind peer-reviewed, open access international circulating professional journal led by a group of research scientists, vascular disease experts and cardiologists coming from North America, Asia and Europe etc. All manuscripts contributed to JCDR are examined by the editorial staff and usually evaluated by 3 peer expert reviewers assigned by the editors with the understanding that they have not been published previously and are not under consideration for publication elsewhere. Journal is being published quarterly
Abstracting and Indexing information
The journal is indexed with Caspur, Chemical Abstracts, CNKI (China National Knowledge Infrastructure), EBSCO Publishing's Electronic Databases, Expanded Academic ASAP, Genamics JournalSeek, Google Scholar, Health & Wellness Research Center, Health Reference Center Academic, Hinari, Index Copernicus, MANTIS, OpenJGate, PrimoCentral, ProQuest, Scimago Journal Ranking, SCOLOAR, SCOPUS, SIIC databases, Summon by Serial Solutions and Ulrich's International Periodical Directory
JCDR publishes a wide range of topics covering basic and clinical research on cardiovascular disease, including but not limited to cardiovascular disease mechanisms, translational and clinical research, cardiac electrophysiology, cardiovascular surgery, resuscitation, hypertension, vascular disease, genetics, molecular biology, biophysics, pharmacology, physiology, stem cells.
Authors should prepare their manuscripts submitted to the journal exactly according to the instructions given here. Manuscripts which do not follow the format and style of the journal may be returned to the authors for revision or may be rejected. The journal reserves the right to make any further formal changes and language corrections necessary in a manuscript accepted for publication so that it conforms to the formatting requirements of the journal. Manuscripts and figures are not returned to the authors, not even upon rejection of the paper.
Author/s is/are responsible for all statements made in their work and obtaining necessary permission to republish any previously published illustrations and/or other relevant materials.
The journal’s full text is available online at WEBSITE
Plagiarism is defined by the World Association of Medical Editors as the appropriation of the language, ideas or thoughts of another without crediting their true source and representation of them as one's own original work.
We deal with this problem and other cases of scientific misconduct at Journal of Cardiovascular Disease Research based on the guidelines prescribed by the Committee on Publication Ethics (COPE), the World Association of Medical Editors (WAME) and the International Committee of Medical Journal Editors (ICMJE).
The journal uses Plagscan for plagiarism screening of submitted articles
Copyright Form can be downloaded from LINK
Manuscripts are considered on the understanding that they contain original material, which the manuscript and material within the manuscript have not been published and are not being considered for publication elsewhere in whole or in part in any language, including publicly accessible web sites or e-print servers, except as an abstract. The authors also certify that any and all other work in preparation, submitted, in press, or published that is potentially overlapping either in the actual data presented or in the conceptual approach is enclosed along with the original submission. Any material within the manuscript that has appeared elsewhere must be cross-referenced and permission to use or adapt the material must be received, in writing from the copyright holder.
Guidelines for Clinical Trials
Research is considered to be a clinical trial if it involves prospective assignment of human subjects to an intervention or comparison group to study the relation between a health-related intervention and a health outcome.
The registry must be accessible to the public at no charge, searchable, open to all prospective registrants, and managed by a not-for-profit organization. The registry must include the following information: a unique identifying number, a statement of the intervention(s), study hypothesis, definition of primary and secondary outcome measurements, eligibility criteria, target number of subjects, funding source, contact information for the principal investigator, and key dates (registration date, start date, and completion date). The registry sponsored by the United States National Library of Medicine (http://www.clinicaltrials.gov) meets these requirements and is recommended by the editors. Other registries are acceptable if they meet these requirements. In addition to www.clinicaltrials.gov, the following registries are recommended by the ICMJE: 1) http://isrctn.org 2) www.umin.ac.jp/ctr/index/htm 3) www.actr.org.au 4) www.trialregister.nl In accordance with the ICMJE’s recommendation, we will also accept registration of clinical trials in any of the primary registers that participate in the World Health Organization’s International Clinical Trial Registry Platform. Primary registers are WHO selected registers managed by not-for-profit entities that will accept registrations for any interventional trials, delete duplicate entries from their own register, and provide data directly to the WHO. Please note that registration in any WHO partner registers is insufficient. The authors will be requested to provide the exact URL and unique identification number for the 7 trial registration at the time of submission. Since this information will be published in a footnote on the first page of the article, we ask that you include the URL and identification number on the title page of your manuscript.
Clinical trial reports should also comply with the Consolidated Standards of Reporting Trials (CONSORT) and include a flow diagram presenting the enrollment, intervention allocation, follow-up, and data analysis with number of subjects for each (http://www.consort-statement.org/?o=1011). Please also refer specifically to the CONSORT Checklist of items to include when reporting a randomized clinical trial.
Results posted in the same clinical trials registry in which the primary registration resides will not be considered prior publication if they are presented in the form of a brief abstract (<500 words or less) or a table.
Guidelines for Studies on Diagnostic Tests
See “The STARD Statement for Reporting Studies of Diagnostic Accuracy: Explanation and Elaboration,” Ann Intern Med. 2003; 138: 40-44.
Guidelines for Human Phenotype-Genotype Association or Linkage Studies
- Report process for selecting genes and SNPs.
- Report Hardy-Weinberg statistics or p-values and method of calculating same.
- Refer to existing public domain websites for the Human Gene Ontology name and the rs number for SNPs.
- Describe genotyping methods. If numerous primers have been used, please include them in an online supplement.
- False positive and false negative concerns.
Given well-described problems with both false positive and false negative associations, phenotype-genotype association studies should meet some or all of the criteria below: 8
- Phenotype is clearly defined, is heritable, and if a quantitative phenotype is reported, reproducibility data are provided.
- The sample size is adequate to detect a SNP or haplotype with a modest effect. For genotype-trait associations, provide an estimate of the effect size that could be detected with power 0.80 or higher with the allele frequency and sample size reported.ı
- Since multiple statistical testing methods are frequently used in genotypingphenotyping studies, please include specifics of the primary model(s) tested. Nonessential secondary models may be published as electronic data supplements. Clinically relevant confounders should be included in multivariable models or residuals.
- Review criteria for human linkage studies.
- Identifying plausible candidate genes under the linkage peak.
- Follow-up fine mapping to narrow the region of linkage, &/or genotyping some of the candidate genes under the linkage peak.
- Replication data from another sample.
The Editorial Process
The manuscript will be reviewed for possible publication with the understanding that it is being submitted to Journal of Cardiovascular Disease Research alone at that point in time and has not been published anywhere, simultaneously submitted, or already accepted for publication elsewhere. The journal expects that authors would authorize one of them to correspond with the Journal for all matters related to the manuscript. All manuscripts received are duly acknowledged. On submission, editors review all submitted manuscripts initially for suitability for formal review. Manuscripts with insufficient originality, serious scientific or technical flaws, or lack of a significant message are rejected before proceeding for formal peer-review. Manuscripts that are unlikely to be of interest to the Journal of Cardiovascular Disease Research readers are also liable to be rejected at this stage itself.
Manuscripts that are found suitable for publication in Journal of Cardiovascular Disease Research are sent to two or more expert reviewers. During submission, the contributor is requested to provide names of two or three qualified reviewers who have had experience in the subject of the submitted manuscript, but this is not mandatory. The reviewers should not be affiliated with the same institutes as the contributor/s. However, the selection of these reviewers is at the sole discretion of the editor. The journal follows a double-blind review process, wherein the reviewers and authors are unaware of each other’s identity. Every manuscript is also assigned to a member of the editorial team, who based on the comments from the reviewers takes a final decision on the manuscript. The comments and suggestions (acceptance/ rejection/ amendments in manuscript) received from reviewers are conveyed to the corresponding author. If required, the author is requested to provide a point by point response to reviewers’ comments and submit a revised version of the manuscript. This process is repeated till reviewers and editors are satisfied with the manuscript.
Manuscripts accepted for publication are copy edited for grammar, punctuation, print style, and format. Page proofs are sent to the corresponding author. The corresponding author is expected to return the corrected proofs within three days. It may not be possible to incorporate corrections received after that period. The whole process of submission of the manuscript to final decision and sending and receiving proofs is completed online. To achieve faster and greater dissemination of knowledge and information, the journal publishes articles online as ‘Articles In Press’ immediately on acceptance.
Authorship credit should be based only on substantial contributions to each of the three components mentioned below:
1. Concept and design of study or acquisition of data or analysis and interpretation of data;
2. Drafting the article or revising it critically for important intellectual content; and
3. Final approval of the version to be published.
Participation solely in the acquisition of funding or the collection of data does not justify authorship. General supervision of the research group is not sufficient for authorship. Each contributor should have participated sufficiently in the work to take public responsibility for appropriate portions of the content of the manuscript. The order of naming the contributors should be based on the relative contribution of the contributor towards the study and writing the manuscript. Once submitted the order cannot be changed without written consent of all the contributors. The journal prescribes a maximum number of authors for manuscripts depending upon the type of manuscript, its scope and number of institutions involved (vide infra). The authors should provide a justification, if the number of authors exceeds these limits.
Contributors should provide a description of contributions made by each of them towards the manuscript. Description should be divided in following categories, as applicable: concept, design, definition of intellectual content, literature search, clinical studies, experimental studies, data acquisition, data analysis, statistical analysis, manuscript preparation, manuscript editing and manuscript review. Authors' contributions will be printed along with the article. One or more author should take responsibility for the integrity of the work as a whole from inception to published article and should be designated as 'guarantor'.
Conflicts of Interest/ Competing Interests
All authors must disclose any and all conflicts of interest they may have with publication of the manuscript or an institution or product that is mentioned in the manuscript and/or is important to the outcome of the study presented. Authors should also disclose conflict of interest with products that compete with those mentioned in their manuscript.
Submission of Manuscripts
Manuscripts must conform to the “Uniform Requirements for Manuscripts Submitted to Biomedical Journals” http://www.icmje.org/. Contributions and Manuscripts must be written in English and submitted exclusively to Journal of Cardiovascular Disease Research. Manuscripts must be typewritten (double-spaced) with liberal margins and space at the top and bottom of the page.
All manuscripts must be submitted online via link provided.
Disclose all possible conflicts of interest (e.g., funding sources for consultancies or studies of products). A brief indication of the importance of the paper to the field of Cardiology is helpful in gaining appropriate peer review.
Preparation of Manuscript
Your Manuscript should be typed, double-spaced on standard-sized – paper (8.5" x 11") with 1" margins on all sides. You should use 12 pt Times New Roman font. Authors should take care over the fonts which are used in the document, including fonts within graphics. Fonts should be restricted to Times New Roman, Symbol and Zapf Dingbats.
Title: Should be in Title Case; The first character in each word in the title have to be capitalized.
Abstract – Limit of 250 Words
A brief summary of the research. The abstract should include a brief introduction, a description of the hypothesis tested, the approach used to test the hypothesis, the results seen and the conclusions of the work.
Please, write no more than six keywords. Write specific keywords. They should be written left aligned, arranged alphabetically in 12pt Times Roman, and the line must begin with the words Keywords boldfaced. A 12pt space should separate the keywords from the affiliations.
Description of the research area, pertinent background information, and the hypotheses tested in the study should be included under this section. The introduction should provide sufficient background information such that a scientifically literate reader can understand and appreciate the experiments to be described. The introduction MUST include in-text citations including references to pertinent reviews and primary scientific literature. The specific aims of the project should be identified along with a rationale for the specific experiments and other work performed.
Materials and Methods
Materials and/or subjects utilized in the study as well as the procedures undertaken to complete the work. The methods should be described in sufficient detail such that they could be repeated by a competent researcher. Please include the company sources for all uncommon reagents (kits, drugs, etc). Illustrations and/or tables may be helpful in describing complex equipment or elaborate procedures. The statistical tool used to analyze the data should be mentioned. All procedures involving experimental animals or human subjects must accompany with statement on necessary ethical approval from appropriate ethics committee.
Data acquired from the research with appropriate statistical analysis described in the methods section should be included in this section. The results section should describe the rational for each experiment, the results obtained and its significance. Results should be organized into figures and tables with descriptive captions. The captions, although brief, should tell the reader the method used, explain any abbreviations included in the figure, and should end with a statement as to the conclusion of the figure. Qualitative as well as quantitative results should be included if applicable.
This section should relate the results section to current understanding of the scientific problems being investigated in the field. Description of relevant references to other work/s in the field should be included here. This section also allows you to discuss the significance of your results - i.e. does the data support the hypotheses you set out to test? This section should end with new answers/questions that arise as a result of your work.
Tables and Figures
Each table must start on a separate sheet. They should be numbered with Roman numerals according to their sequence in the text, and have a short self-explanatory heading. Use SI units. Tables should include vertical rules, but horizontal rules should separate column headings from the content. Authors should keep in mind the page layout of the journal when designing tables. Tables that fit onto one printed page are preferred. Detailed explanations of symbols, units, and abbreviations should follow below the table.
Table and Figure captions
Figure and table captions should be included at the end of the manuscript. Figure captions/legends should include a statement at the end of each caption/legends about reproduction size (e.g. at full page width, at column width). They should be double spaced and typed in the journal format. Explanations should be brief and authors should keep in mind that captions/legends will be placed below figures.
Acknowledgements – Limit of 100 Words
This is a brief section crediting the people who have helped make your manuscript possible and who aided you in your work but are not part of the authorship. Please mention all applicable grants and other funding that supported your work.
It is expected that these articles would be written by individuals who have done substantial work on the subject or are considered experts in the field. A short summary of the work done by the contributor(s) in the field of review should accompany the manuscript.
The prescribed word count is up to 3000 words excluding tables, references and abstract. The manuscript may have about 90 references. The manuscript should have an unstructured Abstract (250 words) representing an accurate summary of the article. The section titles would depend upon the topic reviewed. Authors submitting review article should include a section describing the methods used for locating, selecting, extracting, and synthesizing data. These methods should also be summarized in the abstract.
The journal expects the contributors to give post-publication updates on the subject of review. The update should be brief, covering the advances in the field after the publication of the article and should be sent as a letter to editor, as and when major development occurs in the field.
Reference List: Author/Authors, References should be numbered consecutively in the order in which they are first mentioned in the text (not in alphabetic order). Manuscript with superscript after the punctuation marks. References cited only in tables or figure legends should be numbered in accordance with the sequence established by the first identification in the text of the particular table or figure. Use the style of the examples below, which are based on the formats used by the NLM in Index Medicus. The titles of journals should be abbreviated according to the style used in Index Medicus. Use complete name of the journal for non-indexed journals. Avoid using abstracts as references. Information from manuscripts submitted but not accepted should be cited in the text as "unpublished observations" with written permission from the source. Avoid citing a "personal communication" unless it provides essential information not available from a public source, in which case the name of the person and date of communication should be cited in parentheses in the text. The commonly cited types of references are shown here, for other types of references such as newspaper items please refer to ICMJE Guidelines (http://www.icmje.org or http://www.nlm.nih.gov/bsd/uniform_requirements.html).
In-text citation examples
Correct / Acceptable Format
Noonan Syndrome is a relatively common disorder, seen in 1 in every 1000 to 2500 live births.1 It is an autosomal dominant disease with variable expressivity and no sex or race predilection.2-4 Typically, it is easy to observe, as there are several distinct physical features associated with the disease. These features are similar to Turner syndrome, including shortened stature and neck webbing.5 However, there are some facial dimorphisms unique to Noonan Syndrome, such as a deep philtrum and low-set ears.6,7
JOURNAL REFERENCES [Vancouver Style]
1. Single/Multiple Authors
Parasuraman S, Raveendran R, Kesavan R. Blood sample collection in small laboratory animals. J PharmacolPharmacother 2010;1:87-93
2. More than six authors
Parasuraman S, Sujithra J, Syamittra B, Yeng WY, Ping WY, Muralidharan S,et al. Evaluation of sub-chronic toxic effects of petroleum ether, a laboratory solvent in Sprague-Dawley rats.J Basic Clin Pharm. 2014;5(4):89-97.
3. Organization as Author
Diabetes Prevention Program Research Group. Hypertension, insulin, and proinsulin in participants with impaired glucose tolerance.Hypertension. 2002; 40(5): 679-86.
4. Unknown Author
21st century heart solution may have a sting in the tail. BMJ. 2002; 325(7357): 184-5.
5. Journal article on the Internet
Abood S. Quality improvement initiative in nursing homes: the ANA acts in an advisory role. Am J Nurs [serial on the Internet]. 2002 Jun [cited 2002 Aug 12]; 102(6): [about 3 p.]. Available from:
Note: Plant/Micro organisms, in-vivo, in-vitro should be in italics.
6. Personal author(s)
Murray PR, Rosenthal KS, Kobayashi GS, Pfaller MA.Medical microbiology. 4th ed. St. Louis: Mosby; 2002.
7. Editor(s), compiler(s) as author
Gilstrap LC 3rd, Cunningham FG, VanDorsten JP, editors.Operative obstetrics. 2nd ed. New York: McGraw-Hill; 2002.
8. Author(s) and editor(s)
Breedlove GK, SchorfheideAM. Adolescent pregnancy.2nd ed. Wieczorek RR, editor. White Plains (NY): March of Dimes Education Services; 2001.
9. Organization(s) as author
Royal Adelaide Hospital; University of Adelaide, Department of Clinical Nursing.Compendium of nursing research and practice development, 1999-2000. Adelaide (Australia): Adelaide University; 2001.
10. Chapter in a book
Meltzer PS, Kallioniemi A, Trent JM. Chromosome alterations in human solid tumors. In: Vogelstein B, Kinzler KW, editors. The genetic basis of human cancer. New York: McGraw-Hill; 2002. p. 93-113.
11. Conference proceedings
Harnden P, Joffe JK, Jones WG, editors.Germ cell tumours V. Proceedings of the 5th Germ Cell Tumour Conference; 2001 Sep 13-15; Leeds, UK. New York: Springer; 2002.
N. Khoshakhlagh. The compositions of volatile fractions of Peganumharmala seeds and its smoke.Pharm. D. Thesis, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. (2002).
Website informationCancer-Pain.org [homepage on the Internet]. New York: Association of Cancer Online Resources, Inc.; c2000-01 [updated 2002 May 16; cited 2002 Jul 9]. Available from: http://www.cancer-pain.org/.
Submission of Manuscript
Manuscripts should always be submitted only with the web based Manuscript Submission System : CLICK HERE
All messages and reviews sent electronically will be acknowledged automatically upon receipt.
Note: Do not send hard copies/CDs, until you receive e-mail request from Editorial office.
A timely submission, however, is not a guarantee that your work will be accepted for forthcoming publication. All submissions are peer reviewed by the editorial board and a select group of reviewers. Please make sure that all guidelines are followed carefully. All the accepted articles will be queued for publication and will appear in the futures issues based on the priorities set by the editorial board.
The manuscript should be submitted through Web Based Manuscript Submission ONLY. Hard copies are not accepted.
Check List for Submitting a Manuscript
- Covering letter (first page)
- Copyright Form (Scanned)
- Illustrations (if any)
Status of Manuscript
The corresponding author can check the status of the submitted manuscript on the journal website.
Peng Zhou, MD & Ph.D
Cardiologist, Journal of Cardiovascular Disease Research (JCDR)
Winston-Salem, NC 27103, USA
Chair, Internal Medicine
Oasis International Hospital, Beijing City,
Beijing 100015, China