To determine the relationship between TRUS-Guided Prostatic Biopsy and Serum PSA, Gleason Score, and Grade-Grouping at a Tertiary Centre

Abstract

Aim: To determine the relationship between TRUS-Guided Prostatic Biopsy and Serum PSA, Gleason Score, and Grade-Grouping. Materials and methods: According to the specified criteria, a total of 50 cases were included in the current investigation. Prostatic core samples obtained from various locations inside the prostate were individually placed in containers and forwarded to the Department of Pathology for processing and histological analysis. In order to ensure optimal processing and reporting, a single cassette was equipped with 1-2 (maximum 3) distinct types of cores. Each paraffin block was subjected to cutting at many levels of biopsy core, with a maximum thickness of 4 µm, in order to enhance the likelihood of obtaining a definitive diagnosis of adenocarcinoma. Every slide was stained using the H&E stain. The reporting format for positive cases of prostatic adenocarcinoma adhered to the guidelines set by the College of American Pathologists (CAP).