Kocher Debre Semelaigne Syndrome: A Rare Manifestation of Hypothyroidism

Abstract

Abstract:-
Kocher Debre Semelaigne syndrome(KDSS) is an rare condition in which the main characteristic is muscle pseudohypertrophy which was found to be associated with long standing and the cases of severe hypothyroidism which were untreated[1]
. Here we report the case of a 14 year old female which previously went to endocrinology clinic because she had a very muscular appearance which was associated growth retardation, classical features of hypothyroidism, which showed improvement uponthyroxine supplementation. Pseudo muscular hypertrophy of KDSS is an acquired type of myopathy which is associated with long standing hypothyroidism and is reversible with thyroxine supplement.