STUDY OF ADVERSE REACTIONS OF INDIGENOUS OINTMENT AS LOCAL APPLICATION IN WOUND MANAGEMENT

Abstract

Background: The past decade has seen an explosive growth of wound healing research that promises to facilitate clinical wound repair. Present study was aimed to study adverse reactions of indigenous ointment as local application in wound management. Material and Methods: Present study was prospective, observational study. Patients aged between 18-65 years, either gender, had wound, willing to participate in present study & complete follow-up were included for study. Every time, wound was cleaned with normal saline, dried with gauze & a thin film of ointment covering entire wound surface was applied. Results: In present study, 50 patients with various types of wounds, was carried out to evaluate the efficacy of indigenous topical agent produced from barks of 5 trees. Majority patients were from 26-50 years of age (48 %), were male (63 %) & of non-diabetic aetiology (76 %). In present study,
majority wounds were ulcers (40 %) followed by burns (18 %), post-op wounds (16 %), amputation stumps (14 %) & pressure sores (12 %). In majority of the patient’s wound closure was achieved with split skin grafting (74 5). Common organisms isolated were Pseudomonas Aeruginosa (24 %), Staphylococcus Aureus (20 %) & Proteus Mirablis (10 %). In 80 % patients, systemic antibiotics used in conjunction with local agent. Only local itching was observed as a adverse reaction (2 %) in present study. No local (redness, burning
sensation & pain) or systemic (itching, fever & allergic reactions) were noted in present study. No any significant complications were observed during trial or after trial (during follow up). Conclusion: Indigenous agent is effective and safe for us in the management of
various wounds encountered in surgical practice. It had no adverse reactions and patient compliance and acceptance was good.