Background: Probability of dying of hemodialysis patients can also be caused by heart disease complication. Indonesia and Malaysia are neighboring countries which might have different pattern in probability of dying and survival analysis of diabetic and/ hypertensive patients who undergone hemodialysis with heart disease complication. Objective: To compare probability of dying and survival analysis hypertensive and/diabetic patients who undergone hemodialysis with heart disease complication in Hemodialysis (HD) center Jakarta, Indonesia and Penang, Malaysia. Methods: A cohort prospective study was done among inclusion criteria patients who had been followed up for 9 months. Universal sampling was used to select those hemodialysis patients. Results: There was significant relationship between probability of dying and heart disease comorbidity among hemodialysis patients in HD center Jakarta, Indonesia (hazard: -0.98, hazard ratio: 0.38, 95%Cl for hazard ratio: 0.15-0.98, P < 0.05), while no significant relationship was found between probability of dying and heart disease comorbidity among hemodialysis patients in HD center Penang, Malaysia (hazard: -1.19, hazard ratio: 0.31, 95%Cl for hazard ratio: 0.03-2.74, P > 0.05). Conclusion: Heart disease was one of the risk factors which caused mortality in HD center Jakarta, Indonesia and the percentage to survive for hemodialysis patients who had heart disease in HD center Jakarta was lesser than the patients who did hemodialysis in HD center Penang, Malaysia.