E-ISSN 0976-2833 | ISSN 0975-3583
 

Original Article 


Truncus arteriosus: A major cause of proteinuria in children

Shamsee Ghafari, Majid Malaki.

Abstract
Background: There are many studies about the association of nephropathy with congenital heart diseases (CHD), and the risk factors such as cyanosis and pulmonary hypertension have been evaluated. In our study, we have considered the relation of CHD associated nephropathy with other newer factors and the type of the structural heart defect. Materials and Methods: A prospective cross sectional study was carried out. 48 children were selected on the basis of specifie inclusion criteria, and reviewed over a period of 9 months. Nine different simple and complex structural heart defects were evaluated and compared after obtaining the imaging, blood and urine test results. Results: Significant proteinuria occurred in 8 patients included in the study. More severe forms of pulmonary hypertension were observed in patients suffering from truncus arteriosus (TA); while the least values were detected in cases of pulmonary stenosis (PS) and tetralogy of fallot (TOF). The highest values of protein excretion were seen in patients of TA; and, the lowest values were observed in patients of PS and aortic stenosis (AS). Renal insufficiency was uncommon in infants and children with CHD. Conclusion: TA is an important cause of proteinuria among the infants and children suffering from CHD, probably because of the associated severe pulmonary hypertension (PH) and cyanosis. Also, proteinuria occurred at an earlier age in patients of TA as compared to other conditions, and was also found to be more severe if the TA was associated with moderate to severe tricuspid regurgitation.

Key words: Congenital heart disease, proteinuria, truncous arteriosus


 
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Pubmed Style

Shamsee Ghafari, Majid Malaki. Truncus arteriosus: A major cause of proteinuria in children. J Cardiovasc. Dis. Res.. 2011; 2(4): 237-240. doi:10.4103/0975-3583.89809


Web Style

Shamsee Ghafari, Majid Malaki. Truncus arteriosus: A major cause of proteinuria in children. http://www.jcdronline.org/?mno=93199 [Access: January 16, 2022]. doi:10.4103/0975-3583.89809


AMA (American Medical Association) Style

Shamsee Ghafari, Majid Malaki. Truncus arteriosus: A major cause of proteinuria in children. J Cardiovasc. Dis. Res.. 2011; 2(4): 237-240. doi:10.4103/0975-3583.89809



Vancouver/ICMJE Style

Shamsee Ghafari, Majid Malaki. Truncus arteriosus: A major cause of proteinuria in children. J Cardiovasc. Dis. Res.. (2011), [cited January 16, 2022]; 2(4): 237-240. doi:10.4103/0975-3583.89809



Harvard Style

Shamsee Ghafari, Majid Malaki (2011) Truncus arteriosus: A major cause of proteinuria in children. J Cardiovasc. Dis. Res., 2 (4), 237-240. doi:10.4103/0975-3583.89809



Turabian Style

Shamsee Ghafari, Majid Malaki. 2011. Truncus arteriosus: A major cause of proteinuria in children. Journal of Cardiovascular Disease Research, 2 (4), 237-240. doi:10.4103/0975-3583.89809



Chicago Style

Shamsee Ghafari, Majid Malaki. "Truncus arteriosus: A major cause of proteinuria in children." Journal of Cardiovascular Disease Research 2 (2011), 237-240. doi:10.4103/0975-3583.89809



MLA (The Modern Language Association) Style

Shamsee Ghafari, Majid Malaki. "Truncus arteriosus: A major cause of proteinuria in children." Journal of Cardiovascular Disease Research 2.4 (2011), 237-240. Print. doi:10.4103/0975-3583.89809



APA (American Psychological Association) Style

Shamsee Ghafari, Majid Malaki (2011) Truncus arteriosus: A major cause of proteinuria in children. Journal of Cardiovascular Disease Research, 2 (4), 237-240. doi:10.4103/0975-3583.89809





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